Molecular Formula | C16H21N3O8S |
Molar Mass | 415.42 |
Density | 1.55±0.1 g/cm3(Predicted) |
Boling Point | 814.7±65.0 °C(Predicted) |
pKa | 2.49±0.24(Predicted) |
Physical and Chemical Properties | Chemical properties Its sodium salt dihydrate is monoclinic crystal. Soluble in water, insoluble in ethanol and ether. When the aqueous solution is stable at pH 2.5-8. |
Use | Use of Staphylococcus aureus, Salmonella Typhi, Escherichia coli activity. However, due to low antibacterial activity, clinical not widely used. However, highly efficient derivatives can be obtained by modification, and are currently mainly used as intermediates for the preparation of 7-aminocephalosporanic acid (7-ACA). |
properties
Cephalosporin C (CPC) is a β-lactam antibiotic produced by Cephalosporium acropora (Acremoniumchrysogenum). The structure shows that cephalosporin C uses a dihydrothiazine ring to replace the thiazole ring in penicillin and is connected to the β-lactam ring. It is precisely because of this structural difference that cephalosporin C has stronger stability. It is not easy to be destroyed by penicillinase and can kill many penicillin-resistant bacteria.
production method
produced by fermentation.